![]() ![]() However, some controversies exist in whether women or men have a better outcome among patients undergoing CAG and/or PCI in different countries ( 7, 10– 13). Previous studies reported women undergoing PCI were older, suffered from more comorbidities, and had fewer chance to undergo PCI or other bypass treatments compared with men ( 8– 10). Coronary angiography (CAG) is the reference standard for CAD diagnosis and percutaneous coronary intervention (PCI) remain the major revascularization strategy for patients with CAD, with an estimated five million procedures performed worldwide each year ( 3– 7). Women have nearly 90% higher risk of in-hospital mortality and over 1-fold increased risk of major bleeding after PCI compared with men.Ĭoronary artery disease (CAD) is a major cause of death and disability among both women and men globally ( 1, 2). After adjustment, women had a higher risk in the major bleeding (adjusted odds ratio, 2.04 ), and the in-hospital mortality (adjusted odds ratio, 1.87 ).Ĭonclusion: Among our Chinese cohort, women are older with more chronic comorbidities, receiving less PCI procedure and similar discharge medication treatment. 0.3%, P = 0.033) but higher in-hospital mortality (1.2 vs. In addition, women undergoing PCI had mildly lower rate of major bleeding (0.2 vs. Among women undergoing PCI they received similar discharge medication treatment. Women received less CAG and PCI procedures. ![]() 60.8 years), had more chronic comorbidities and lower PCI rate for stable coronary artery disease (CAD) than men (52.8 vs. Results: Totally 141,459 patients underwent CAG (44,362 women), of which 69,345 patients underwent PCI (15,376 women). Clinical characteristics, treatment (discharge medication and PCI) and in-hospital outcomes (mortality and major bleeding) were compared between women and men. Methods: We analyzed patients undergoing CAG and/or PCI in this multi-center registry cohort study Cardiorenal ImprovemeNt II (CIN-II) in 5 Chinese tertiary hospitals from 2007 to 2020. We aimed to investigate the sex differences in characteristics, treatments and outcomes among patients undergoing CAG and PCI in a large Chinese cohort. 9Guangdong Provincial People's Hospital, School of Medicine, South China University of Technology, Guangzhou, Chinaīackground: Whether women have a higher risk of adverse events compared with men following coronary angiography (CAG) and percutaneous coronary intervention (PCI) remains controversial.8Department of Cardiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.7Department of Cardiology, Yangjiang People's Hospital, Yangjiang, China.6Department of Cardiology, Shenzhen People's Hospital, Shenzhen, China.5Department of Cardiology, Maoming People's Hospital, Maoming, China.4Department of Information Technology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.3The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.2Department of Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.1Department of Cardiology, Guangdong Provincial People's Hospital, Guangdong Cardiovascular Institute, Guangdong Academy of Medical Sciences, Guangzhou, China.Shi-Qun Chen 1,2 †, Jin Liu 1,2 †, Yang Zhou 1,2 †, Zhi-Dong Huang 1,2, Yun Xie 1,2, Hao-Zhang Huang 1,2,3, Xiao-Ming Yan 4, Yong-Yi Xie 4, Peng-Fei Hao 4, Yan Liang 5, Shao-Hong Dong 6, Xiao-Yu Huang 7, Li-Ling Chen 8, Ning Tan 1,2,3,9 *, Yong Liu 1,2,3,9 * and Ji-Yan Chen 1,2,3,9 * ![]()
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